by Michael A. Jenike, M.D.
Professor of Psychiatry
Harvard Medical School
Chairman, OC Foundation Scientific Advisory Board
Overview of OCD
Obsessive-Compulsive Disorder (OCD) is a potentially devastating illness that can result in considerable social and
economic disability for both patients and their family members. OCD
is usually treated with a combination of specific behavioral therapies, called exposure
and response prevention, and medications. It is important to note that many psychoactive
medications are not likely to help OCD symptoms, but that a number of partially-effective
drugs have now been carefully evaluated. The treatment, however, for most OCD patients
should involve the combination of behavior therapy with medications. This article will
focus on medications, but that is not meant to diminish the importance of behavior
What kinds of medications may help OCD?
The majority of the drugs that help OCD are classified as antidepressants. It is
important to note that depression commonly results from the disability produced by OCD,
and that doctors can treat both the OCD and depression with the same medication.
There are also a number of disorders that are possibly related to OCD, such as
compulsive gambling and sexual behaviors, trichotillomania, body dysmorphic disorder,
compulsive eating, nail biting and compulsive spending. There is some evidence that the
medications and behavior therapies discussed in this article will help some of these
patients also, but more research is needed in this area to give firm recommendations.
Do all antidepressants help OCD symptoms?
No! Some commonly used antidepressants have no effect whatsoever on OCD symptoms.
Drugs, such as imipramine (Tofranil) or amitriptyline (Elavil), that are good
antidepressants, only rarely improve OCD symptoms.
Which drugs help OCD and how do we know these drugs are effective?
There are five drugs that have been shown to be useful in very good double-blind (both
physician and patient unaware of whether patient is receiving drug or placebo [inert sugar
pill]) placebo-controlled (about half of the patients receive drug and the other half
placebo or inactive pill) studies. This is a very good way to evaluate drugs since
improvements can be evaluated in an unbiased manner and drug effectiveness can be
The five drugs that have been shown to be effective in such studies include:
fluvoxamine (Luvox), fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil), and
clomipramine (Anafranil). Anafranil has been around the longest and is the best studied
throughout the world, but there is growing evidence that the other drugs are as effective.
In addition to these carefully studied drugs, there are hundreds of case reports of
other drugs occasionally being helpful. There are small series of patients reported that
suggest that venlafaxine (Effexor) may also be somewhat effective, but large scale
controlled trials are lacking.
Why do these drugs help?
It remains unclear as to why these particular drugs help OCD while similar drugs do
not. Each has potent effects on a particular neurotransmitter, or chemical messenger, in
the brain called serotonin. It appears that potent effects on brain serotonin are
necessary (but not sufficient) to produce improvement in OCD. Serotonin is one of several
neurotransmitter chemicals that nerve cells in the brain use in communicating with one
another. Unlike some other neurotransmitters, its receptors are not localized in a few
specific areas of the brain; hence, its uptake and release affects much of our mental
life, including OCD and depression.
Neurotransmitters such as serotonin are active when they are present in the
"gap" (referring to the synaptic cleft) between nerve cells. Transmission is
ended by a process by which the chemicals are taken back up into the transmitting cell.
The anti-obsessional drugs are called "serotonin reuptake inhibitors" or SRIs;
they work by slowing the reuptake of serotonin, thus making it more available to the
receiving cell and prolonging its effect on the brain. We think that this increased
serotonin produces changes, over a period of a few weeks, in receptors (areas where
serotonin attaches) in some of the membranes of the nerves. We also believe that these
receptors may be abnormal in patients with OCD and that the changes that occur in them due
to these medications at least partly reverse the OCD symptoms. This is only part of how
drugs work; it is very likely that other brain chemicals in addition to serotonin are
involved. In fact, when activity in the brain's serotonergic system is altered, this
changes the activity of other brain systems.
Experiments have been done with drugs that directly stimulate components of the
serotonin system in the brain, and it was found that such so-called serotonergic agonists
actually make OCD symptoms worse. However, after patients are successfully treated for
OCD, these agonists do not worsen OCD symptoms; thus suggesting that there may be some
changes in the brain's serotonergic system with effective drug treatment that somehow
results in improvement in symptoms.
Don't worry if this does not make sense to you. Researchers do not know how the drugs
work and that is why this is all so confusing. The good news is that we do know, after
decades of research, how to treat patients, even though we do not know exactly why our
At what dosages are these drugs used?
As a general rule, it appears that for most people high dosages of these drugs are
required to obtain antiobsessional effects. The studies done to date suggest that the
following dosages may be necessary: Luvox (up to 300 mg/day), Prozac (40-80 mg/day),
Zoloft (up to 200 mg/day), Paxil (40-60 mg/day), Anafranil (up to 250 mg/day). Where a
lower dosage was listed, at least some of the studies have suggested that a dose lower
than the minimum was not significantly better than placebo.
I have also seen a very small number of patients who have not responded to large
dosages of each of these medications, but who improved on extremely low doses, such as
5-10 mg/day of Prozac or 25 mg/day of Anafranil. These patients have not been carefully
studied and, to my knowledge, these low-dosage responders are not reported in the
psychiatric literature. If patients fail to improve with high dosages of the above
medications, it is probably worth a trial of a very low dose.
Are there side effects?
Each of these drugs has side effects, and it is quite unusual for an individual patient
not to have one or more side effects. As with all drugs, the patient and physician must
weigh the benefits of the drug against the side effects. It is important for the patient
to be open and forceful about problems that may be caused by the medication. Sometimes
just an adjustment in dosage or switch in the time of day that one takes the medication is
all that is required.
Luvox, Prozac, Paxil, and Zoloft are called SSRIs or selective serotonin reuptake
inhibitors, while Anafranil is an older tricyclic antidepressant or SRI (serotonin
reuptake inhibitor) that has effects on other chemical messengers besides serotonin and is
thus not selective for serotonin.. All of these drugs commonly produce sexual side effects
in both sexes that may range from lowering of sexual drive to delayed ability to have an
orgasm to complete inability to have an erection or orgasm. Interestingly, there is an
uncommon side effect that has been reported where patients have spontaneous orgasms while
yawning. This must be quite uncommon since no patient has ever told me of such a symptom,
and when patients yawn in my office, they always look bored, not excited. Occasional
patients report increased interest in sexual activity. Although it may seem embarrassing,
you should tell your physician about sexual difficulties so that he or she can help you
figure out how best to deal with them. These side effects are so common that your
psychiatrist will not be surprised. There have recently been a few reports of patients who
were having sexual difficulties on these drugs who stopped taking them on Fridays and
Saturdays and were able to at least enjoy successful sexual activity on the weekends. It
appears so far, that this approach has not produced a relapse in symptoms, but this may be
reported as people try this more often. Also, with Prozac this approach has not been as
effective since it is such a long acting compound.
The SSRIs also commonly cause nausea, inability to sit still, sleepiness in some
individuals, insomnia in others, and a heightened sense of energy. The tricyclic Anafranil
may cause pronounced effects like drowsiness, dry mouth, racing heart, memory problems,
concentration difficulties, and problems with urination (mostly in men). Sometimes weight
gain is a problem and a strict diet may be needed if appetite is increased. There are many
other less common side effects with these drugs that your physician may discuss with you.
As a general rule, these drugs are very safe, even with long term use, and all of the side
effects completely reverse when the drugs are stopped; thus there is no evidence that they
do permanent damage to the body.
What if I cannot tolerate even the smallest pill size of the medication?
Occasional patients are very sensitive to medications and cannot tolerate even the
lowest dosage that comes in pills. Many of the pills can be broken in half to allow for
lower dosages. There is also a liquid form of Prozac that has allowed many patients to
gradually increase the dosage to therapeutic levels. Often if patients can start at very
low dosages (eg, 1-2 mg per day) and very slowly increase the dose, they will eventually
be able to tolerate the medication. This technique has proven so successful for many
people that there is now a fan club of those helped by this approach.
Many patients have been able to use liquid Prozac. For example, one woman who was
started on Prozac 20 mg/day, complained of very bothersome side effects such as increased
anxiety, shakiness, and terrible insomnia. She also felt it had made her OCD worse. In
addition, she had horrible side effects from even 12.5 mg of Anafranil, and later with low
dosages of Paxil and Zoloft. She then started 1-2 mg/day of liquid Prozac that she had
heard was good from other patients that she met over a computer bulletin board. She felt
no side effects, and over a period of a few weeks, she again got up to 20 mg/day without
the previous side effects that she had felt on this dose in the past. She continued to
increase the Prozac to 60 mg/day over a couple more months, and her OCD gradually improved
Thus, careful and gradual increases in dosage with liquid medication may allow some
medication-sensitive patients to reach therapeutic levels.
Do antiobsessional medications cause long-term, irreversible side effects?
As far as we know there are no irreversible side effects caused by the standard
antiobsessional drugs. Many patients have used them for years without difficulties. Some
of the drugs that are occasionally used - such as the antipsychotic (or sometimes called
neuroleptic) drugs like haloperidol (Haldol), chlorpromazine (Thorazine), thioridazine
(Mellaril), and trifluoperazine (Stelazine) - can produce irreversible neurologic
problems, such as persistent tremor or tongue thrusting. These drugs are best avoided in
patients with the usual forms of OCD; if they are used, it should generally be for only a
few weeks. Occasionally patients need to remain on these potentially troublesome drugs for
longer periods of time. For example, in OCD patients that also have tics (brief muscle
jerks, such as repetitive eye blinks, nervous cough, or shoulder shrugs), there is now
evidence that very low doses of these neuroleptic drugs added to ongoing SRI medication
helps OCD symptoms. In OCD patients without tics, there is no evidence that neuroleptics
are helpful and are best avoided. There are newer neuroleptic agents, like clozapine
(Clozaril) and risperidone (Risperdol) that may have fewer of these types of neurologic
problems, that may be helpful when added to SRI treatment. These new drugs should not be
used alone since they have been associated with worsening of OCD symptoms when not taken
in combination with a SRI.
Who should not take antiobsessional medications?
In general, we try not to give antiobsessional medications to women who are pregnant or
are breast-feeding. Since we do not clearly understand the long-term effects of these
drugs on a fetus or infant, this is the most prudent course of action. If severe OCD
cannot be controlled any other way, however, these medications seem to be safe and many
pregnant women have taken them without difficulty. If there were risk to the fetus, it is
likely that most of the risk would be during the first 3 months of pregnancy when the
baby's brain is developing. Some OCD patients are able to use the behavioral techniques
of exposure and response prevention to avoid medications at least during the initial 3
months of pregnancy. If your OCD is very severe, you may need to take a medication
throughout the course of pregnancy.
In very elderly patients, it is best to avoid Anafranil as the initial drug since it
has side effects that can interfere with thinking and can cause or worsen confusion in the
elderly. Some of the other antiobsessional drugs like Prozac, Zoloft, Luvox, and Paxil can
be used in the elderly, but greatly reduced dosages are usually needed.
Although these drugs can be taken by patients with heart disorders, special caution is
required, and close monitoring with frequent cardiograms (ECGs) may be necessary.
Should I take antiobsessional medications only when I am feeling stressed?
No. This is a common mistake. These medications are meant to be taken on a regular
daily basis to maintain a constant level in your blood stream. They are not taken like the
typical antianxiety agents; when you feel upset or anxious. It is best not to miss dosages
if possible. Having said this, it is unlikely that any adverse effect on OCD will occur if
a daily dose is missed occasionally and sometimes missed dosages are prescribed by your
doctor to help manage troublesome side effects, such as sexual dysfunction (see later
What kind of doctor should I look for to prescribe these antiobsessional medications?
Although any licensed physician can legally prescribe these drugs, it is probably best
to deal directly with a board-certified psychiatrist who understands OCD. A list of
psychiatrists with special interest in OCD can be obtained from the OC Foundation. Keep in
mind, however, that these are physicians who have expressed an interest in OCD and that
the Foundation has not evaluated them in any way. Legally, they are obligated to list any
psychiatrist who expresses an interest in the disorder. It is also important to find a
psychiatrist who is also a psychopharmacologist; that is, one who has special knowledge
about the use of drugs to treat psychiatric disorders.
What if I feel as if I've failed because I need a drug to help me?
A useful way of thinking about the use of medication for OCD is to compare your illness
with a common medical disorder such as diabetes. There is growing evidence that OCD is, in
fact, a neurologic or medical illness and not simply a result of some problem in the
environment or of improper upbringing. As with the diabetic who needs insulin to live a
normal life, some OCD patients need anticompulsive medication to function normally;
diabetics also often feel angry and upset about having to take insulin. There is no
evidence that OCD is a result of anything that the patient has done, and it is best to
consider it a chemical or neurologic disorder affecting a part of the brain.
What if I am afraid to take medications because of my obsessional fears about drugs?
Usually with reassurance from a doctor that you trust, your fears can be overcome. If
you still refuse to take medication, behavior therapy can be started first, and part of
the therapy can focus on your reluctance to take medication. Our experience indicates that
the combination of medication and behavior therapy will maximize your chances for
How much does it cost to take these drugs?
Unfortunately, these drugs are very expensive and can cost the patient up to $6 or $7
per day for larger doses. When the patent expires on each of these drugs, other companies
can make generic forms of each drug, and then the prices will fall. However, this will not
happen for many years with the drugs currently available.
Why are they so expensive?
One can think of all sorts of sinister reasons why pharmaceutical companies charge so
much for these medications, but we must keep in mind that it costs many millions of
dollars to bring just a single drug to market in the United States. Most drugs do not make
it to the market and represent a lost investment; but if the pharmaceutical companies do
not try out new agents, no progress in this area is likely. These companies spend millions
in research trying to identify new compounds that may have therapeutic value. Without
pharmaceutical companies, there would likely be few, if any, advances in clinical
pharmacology in the United States, and we would not have new drugs available to us.
Pharmaceutical companies are also heavily involved in promoting awareness of the various
diseases, including OCD, for which they have a medication. These promotions (television,
radio, print) are of benefit to patients as this is often the manner in which they
discover that they have OCD, that it has a name, and that it can be treated.
Pharmaceutical companies have even been active in promoting non-drug treatments, such as
behavior therapy, when they have nothing financially to gain. They also sponsor
educational programs to physicians and have been instrumental in spreading the knowledge
base about OCD to both physicians and patients. They have been financial backers of
organizations like the national Obsessive Compulsive Foundation.
Can I get the drugs if I am poor?
Often pharmaceutical company representatives visit physicians and leave free samples of
medications. Physicians may give these samples to patients who cannot afford the expense
of the medications.
In addition, each of the pharmaceutical companies involved in the production of the
five primary antiobsessional drugs offers free drug to patients who are truly quite poor.
The Pharmaceutical Manufacturers Association publishes a directory of indigent programs
for those who cannot afford medications. Physicians can request a copy of the guide by
calling (800) PMA-INFO. To get more information on each company's programs, you or your
physician can contact the indigent patient program at the following companies directly:
Luvox: Solvay Patient Assistance Program - 800-788-9277
Prozac: Lilly Cares Program - 800 -545-6962
Paxil: SmithKline Paxil Access To Care Program - 800-546-0420 (patient requests) 215-751-5722 (physician requests)
Zoloft: Pfizer Indigent Patient Program - 800 -646-4455
Anafranil: Ciba-Geigy Patient Support Program - 800-257-3273; 908-277-5849
How long does it take antiobsessional medications to work?
It is important not to give up on a medication until you have been taking it at a
therapeutic dose for 10 to 12 weeks. Many patients feel no positive effects for the first
few weeks of treatment, but then they may improve greatly. Unfortunately during the early
part of treatment, patients may only have side effects and no positive results, and
sometimes physicians forget to tell patients about this lag in response. We do not know
why the medications take so long to work for OCD. Keep in mind that even many
psychiatrists give up on the medications after 4 to 6 weeks, since this is the time it
takes for depressed patients to improve. Thus, you may have to remind your psychiatrist to
keep you on the medication longer.
How helpful can I expect these medications to be?
In the large studies that have been done, each medication helps about 75% to 85% of the
patients at least a little. About 50% to 60% of patients in each trial had at least a
moderate response to medication. Some patients have no response at all. If you do not
respond to the first medication, then it is important to go on to the next. I have seen
patients who have had no response to three of the above medications, who had a wonderful
response to the next one. There are also techniques of combining medications that may
increase the response magnitude and rate (see next section). One patient wrote to me:
seeking an effective medication for OCD is a lot like dating to find a mate; don't be
afraid to shop around and try different meds till you find one that works for you!
What about augmenting one drug with another?
The best augmenting technique is to add behavior therapy to ongoing drug treatment.
However, to boost a drug's effect, we sometimes combine two or more medications together.
For example, some people respond to combining Luvox or Prozac with Anafranil. It is
important for the physician to keep in mind that Anafranil's blood level can be
dramatically increased by adding one of the other drugs, so it is important to keep
Anafranil's dose low at least during the initial stages of treatment. Sometimes blood
levels are helpful, but most of the time a good clinician can just follow side effects and
symptom reduction to find the correct dosage.
Other drugs are sometimes combined with ongoing SRI medications. Some that have
commonly been used include: buspirone (Buspar), lithium carbonate (Eskalith), clonazepam
(Klonopin), methylphenidate (Ritalin), fenfluramine (Pondamin), and other antidepressants
(eg, trazodone, bupropion, desipramine, etc). The controlled trials that have been done
with these augmenting agents have been largely disappointing, but since occasional
patients respond to the addition of a second drug, clinicians frequently try this
Are there other medications that can be used to treat OCD?
Yes, there are drugs that are occasionally helpful in individual patients besides the
ones already mentioned. For example, some patients may be helped by drugs called monoamine
oxidase inhibitors (eg, Nardil [phenelzine], Parnate [tranylcypromine]) that work in a
different way than the previously mentioned drugs. These drugs inhibit one of the enzymes
that degrades the chemical messengers in the nerve gaps, thereby lengthening the time that
the messenger can be active. There is some anecdotal evidence that OCD patients who also
have panic attacks or prominent concerns with symmetry may be more likely to improve with
monoamine oxidase inhibitors. With these drugs, certain foods and medications cannot be
taken with them or potentially fatal reactions can occur. They are particularly dangerous
in combination with the SRI medications so these must be stopped for at least 2 weeks (5
weeks for Prozac which is longer lasting) prior to starting monoamine oxidase inhibitors.
The other antidepressants occasionally help, but chances of this are quite small.
Will I have to take antiobsessional medications forever?
No one knows yet how long patients should take these medications once they have been
effective. Some patients are able to discontinue medications after a 6- to 12-month
treatment period. However, it does appear that over half of OCD patients (and maybe many
more) will need to be on at least a low dosage of medication for years, perhaps even for
life. It seems likely that the risk of relapse will be lower if patients learn to use
behavior therapy techniques while they are doing well on medications and if medication is
tapered very slowly (even over several months). The behavioral techniques may enable
patients to control any symptoms that return when they stop taking medication. Typically,
after medications are stopped, symptoms do not return immediately, but may start to return
within a few weeks to a few months.
When one of these drugs is working and then discontinued and symptoms return, the vast
majority of patients have a good response upon reinstitution of the medication. However, I
have now seen a few patients who did not respond when the discontinued drug was restarted.
Can I drink alcohol while on medication?
Many patients drink alcohol while on these medications and tolerate it well. It is
important to keep in mind that alcohol may have a greater effect on individuals who are
taking medication; that is, one drink could affect an individual as if it were two drinks,
etc. Also, it is not known if alcohol can counteract some of the therapeutic effects of
the medication, so it may be worth trying not to drink alcohol during the first couple of
months after starting medication.
Do I need other treatments in addition to medications?
As noted earlier, most psychiatrists and behavior therapists today believe that
combining behavior therapy, consisting of exposure and response prevention, and medication
is the most effective approach.
What is Behavior Therapy?
Traditional psychotherapy, aimed at helping the patient develop insight into his or her
problem, is generally not helpful specifically for OCD symptoms themselves. However,
traditional psychotherapy may be of benefit as part of a treatment package for patients
who have been ill and isolated for many years or for those whose illness started at an
early age. On the other hand, behavior therapy consisting of techniques called
"exposure and response prevention" is effective for many people with OCD. In
this approach, the patient is deliberately and voluntarily exposed to feared objects or
ideas, either directly or by imagination (the exposure component), and then is discouraged
or prevented (with the patient's permission) from carrying out the usual compulsive
response (the response prevention component). For example, a compulsive hand washer may be
urged to touch an object believed to be contaminated, and then may be denied the
opportunity to wash for several hours. When the treatment works well, the patient
gradually experiences less anxiety from the obsessive thoughts and becomes able to do
without the compulsive actions for extended periods of time.
Studies of behavior therapy for OCD have found it to produce-lasting benefits. To
achieve the best results, a combination of factors is necessary: The therapist should be
well trained in the specific method developed; the patient must be highly motivated; and
the patient's family must be cooperative. In addition to visits to the therapist, the
patient must be faithful in fulfilling "homework assignments." For those
patients who complete the course of treatment, the improvements can be significant.
With a combination of drug and behavioral therapy, the majority of OCD patients will be
able to function well in both their work and social lives. The ongoing search for causes,
together with research on treatment, promises to yield even more hope for people with OCD
and their families.
How are OCD and depression related?
Approximately 2/3 of OCD patients have also suffered at least one major depression at
some point in their life. About 1/3 are depressed when they present to us for treatment.
Some schools of thought feel the OCD causes the depression while others believe the OCD
and depression simply tend to co-exist. Most patients tell me that their OCD symptoms came
first, and then depression began when they were unable to handle the OCD.
What are some signs of depression?
Loss of appetite
Early morning awakenings
Lack of energy
Too much sleeping
Crying, especially without knowing why
Feelings of hopelessness
Feelings of helplessness
Lack of interest in things which formerly interested person
Lack of enjoyment of life
The presence of one or more of these symptoms does not necessarily indicate the
presence of depression, but if several are present, you may be depressed.
What if my OCD gets better, but I remain depressed?
It sometimes happens that OCD improves and depression persists. Occasionally a second
drug is added to combat the depression; sometimes your doctor can assist you in finding
other reasons why depression persists.
How do I find treatment?
One of the easiest ways to find a mental health professional in your area who has
experience dealing with OCD patients is to contact the OC Foundation in Connecticut
(203-878-5669), or call the Association of Advancement of Behavior Therapy. See
The OC Foundation also will send you a packet of information and a bi-monthly
newsletter for the membership fee of $30.00.
How can I reach the OC Foundation?
By postal mail:
P.O. Box 70
By telephone: 1-203-878-5669
By fax: 1-203-874-2826
By InfoLine: 1-203-874-3843
What are some titles of books and other information about OCD?
Getting Control: Overcoming Your Obsessions and Compulsions by Lee Baer, PhD.
Stop Obsessing!: How to Overcome Your Obsessions and Compulsions by Edna Foa, PhD
and Reid Wilson, PhD.
Over and Over Again: Understanding Obsessive Compulsive Disorder by Fugen Neziroglu,
PhD and Jose A. Yaryura-Tobias, MD.
When Once Is Not Enough: Help for Obsessive Compulsives by Gail Steketee, PhD and
Kerrin White, MD.
Funny You Don't Look Crazy: Life With Obsessive Compulsive Disorder by Connie
Obsessive Compulsive Disorder: A Guide: Dean Foundation, Madison, WI by John H.
Greist, MD (Dean Foundation), 1992, (Comment: This booklet is available through the OC
Polly's Magic Games: A Child's View of Obsessive Compulsive Disorder by Connie
Foster. Dilligaf Pub, 1994.
New Developments in the Biology of Mental Disorders. Research and Education Assoc.
1995. Section on government funding/research.
Obsessive-Compulsive Disorders: Theory and Management. Second Edition, by Jenike MA,
Baer L, Minichiello WE, (editors), Chicago, Il, Year Book Medical Publishers, 1990. (A
Living with Prozac and other selective serotonin reuptake Inhibitors by Debra
Elfenbein. Harper Pub. San Francisco 1995. 303 pages $9. Personal accounts of life on
Understanding Obsessive Compulsive Disorder. by Jenike MA, Asberg M, (editors),
Stuttgart, Hogrefe & Huber Publishers, 1990.
Obsessional Disorders. by Jenike MA, (editor), Psychiatric Clinics of North
America. Vol 15, Number 4, December 1992.
The Touching Tree. Jim Callner, writer/director, Awareness films.
Distributed by the OC Foundation, Inc., Milford, CT. (About a child with OCD)
Jenike MA. Health Care Reform for Americans with Severe Mental Illnesses: Report of the
National Advisory Mental Health Council: Obsessive-compulsive disorder: Efficacy of
specific treatments as assessed by controlled trials. Psychopharmacology Bulletin.
Are there other resources for people with OCD and related disorders?
Trichotillomania Learning Center
1215 Mission St, Suite 2
Santa Cruz, CA 95060
Membership: $35 includes information packet and bimonthly newsletter
Dean Foundation for Health and Education
8000 Excelsior Drive
Madison, WI 53717
Ask for "Obsessive Compulsive Disorder: A Guide: by John H. Greist. OC Info Center
has ability to do computer searches on latest OCD research and clinical papers. Computer
data base of over 4,000 references updated daily. Computer searches done for nominal fee.
No charge for quick reference questions. Maintains physician referral and support group
National Institute of Mental Health
c/o Research on OCD
Building 10, Rm 3D41
10 Center Drive MSC 1264
Bethesda, MD 20892
Information Resources and Inquiries Branch
5600 Fishers Lane
Rockville, MD 20857
Anxiety Disorders Association of America
6000 Executive Blvd.
Rockville, MD 20852
1-900-737-3400/24 hr. service @ $2.00/minute
Makes referrals to professional members and to support groups. Has a catalog of
available brochures, books, and audiovisuals. Has an annual meeting where professionals
and patients meet together.
Obsessive Compulsive Anonymous
PO Box 215
New Hyde Park, NY 11040
California Affiliate of the OC Foundation
18653 Ventura Blvd., Suite 414
Tarzana, CA 91356-4174
National Alliance for Mentally Ill
200 North Globe Rd, Suite 1015
Arlington, VA 22203
Freedom From Fear
308 Seaview Avenue
Staten Island, NY 10305
Center for Help for Anxiety/Agoraphobia through New Growth Experience
128 Country Club Drive
Chula Vista, CA 91911
Association for Advancement of Behavior Therapy
305 7th Ave. Suite 1601
New York, New York 10001-6008
Membership listing of mental health professionals focusing in behavior therapy.
Tourette Syndrome Association, Inc.
42-40 Bell Boulevard
New York, NY 11361-2874
Publications, videotapes, and films available at minimal cost. Newsletter goes to
members who pay an annual fee of $35.00.